Job Scope & Purpose:
Are you an experienced and passionate Scientist with abilities including design, implementation, and execution of Biochemical Assays in a High-throughput setting? If so take note of Stratacuity's amazing Oncology drug development client's new role.
Don't miss this opportunity to work on a top-notch oncology team in defining the new standard in cancer drug discovery. This dynamic team is ideally seeking to add a Scientist that can work and collaborate with the Biomolecular and HT Screening Group, a pivotal team responsible for assay development, High Throughput Screening, and hit-to-leads support for their pipeline. This role will also help evolve our client's hit identification and hits-to-leads support through embracing novel assay technologies. As a multitasking team member you'll work on enhancing the overall process and actively drive partnerships with Biology and Chemistry to lead to pipeline strategy and success. Come join one of Boston's best Cancer drug development teams and impart your assay development expertise when it comes to Biochemical and High-throughput Screening technologies.
Primary Job Responsibilities:
Ability to provide a mentorship presence in the Biomolecular Screening group, responsible for assay design, high-throughput screening (HTS), and hit-to-lead program support
Must be very capable of driving collaboration with cross-functional teams in Medicinal Chemistry and Biology; knowledge of the drug discovery process and experience in oncology and/or inflammatory drug discovery is preferred
Extensive understanding of biochemical assays, associated assay technologies and instrumentation is a must
Extensive experience of running both HTS campaigns and IC50 determinations across panels of assays
A detailed knowledge of high-throughput data management, data flow, analysis, and visualization is imperative
Familiarity with robotic automation desired, preferably HighRes Biosolutions systems and "Cellario" software suite
Expertise with high content cellular assay development and implementation
Hands-on experience in the execution of high-quality mechanistic assays would be a significant advantage (e.g. Determination of Ki, Kd, drug residence times, slow/irreversible binding and mode of inhibition from catalytic and binding studies)
Experience with application of biophysics, structural biology, and molecular protein complexes to optimize clinical candidates would be a significant advantage
Responsible for establishing, monitoring and maintaining protocols and QC controls in the laboratory environment
Primary Job Requirements:
Ph.D. 0-3 years or B.Sc/M.Sc 7-10 years of Biotech or Pharmaceutical industry experience in HTS, assay design, enzymology/mechanism of action and automation technologies
Expert knowledge of Biochemistry and Cell Biology
Skills Required: Assay Development, Automation, and Enzymology Assay Development
Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
PROVEN SCIENTIFIC PLACEMENT™