Associate Scientist, Oligonucleotide Chemistry
Associate Scientist, Oligonucleotide Chemistry 1344148
Location: Cambridge, MA (Onsite)
Science: CRISPR/Cas 9
Therapeutic Area: Neuromuscular Diseases
Job Overview: The Associate Scientist will join the RNA medicinal chemistry team and work with an enthusiastic team of highly skilled scientists to advance the company’s cutting-edge gene editing drug discovery programs.
Responsibilities:
- Proficient in automated high throughput synthesis, purification, and analysis of novel oligonucleotides with various chemical modifications and scales.
- Operate, maintain & troubleshoot oligonucleotide synthesis platforms (MerMade 12 and Dr. Oligo 48, etc.), HPLCs, LCMS and other scientific equipment.
- Oligonucleotide synthesis method and process development for improved oligonucleotide/ conjugates synthesis, purification, and analysis.
- Track progress, generate regular status updates, and communicate the progress and present data.
Qualifications:
- BS or BA in Chemistry, Biochemistry, or related fields with 1 – 3 years chemistry laboratory experience in an industrial or academic setting or M.S. in Chemistry, Biochemistry, or related fields with excellent understanding of nucleic acids and analytical chemistry and 1 – 2 years chemistry laboratory experience.
- Experience in solid-phase synthesis, purification and downstream processes of oligonucleotides is required.
- Experience in handling, troubleshooting and routine maintenance of critical instrumentation such as automated oligonucleotide synthesizers, HPLCs and LC-MS etc.
- Experience working in chemistry laboratory and preparation of phosphoramidite and reagent solutions.
About Stratacuity:
Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
PROVEN SCIENTIFIC PLACEMENT™
Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.
EEO Employer
Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystems.com or 844-463-6178.