Director/Sr. Director, Immune Cell Therapy Research

Cambridge, MA

Director/Sr. Director, Cell Therapy Immunology 1118937

Job Scope & Purpose:

Stratacuity’s exclusive client is developing a novel class of allogenic, off the shelf, CAR-NK cell therapies developed to treat a broad range of both solid and liquid cancers. Our client’s proprietary capabilities allow them to harness the cancer-fighting properties of NK cells, enhance and tailor their effectiveness with advanced techniques. This team is being led by a proven group who have been pioneers in the cell therapy space and have already driven multiple entities into the clinic and through approval.

Our Client is seeking a highly motivated and accomplished cell therapy expert to lead the development and implementation of preclinical candidate selection and IND-Enabling research activities. Reporting direct to the SVP, Research the individual will be an SME in immuno-oncology and will manage the output of multiple team members.

Primary Job Responsibilities:

  • Drive and develop pipeline strategy for current and future engineered Immune Cell Therapy assets in Oncology
  • Review and integrate knowledge from diverse sources to drive activities for Candidate Selection
  • Support development of pre-clinical program blueprints, including articulation of key scientific question, assessment of program milestones and risks, and development of project roadmaps, flow charts, timelines, and go/no-go criteria to move projects through key project stage gates.
  • Provide subject matter expertise and strategic vision to matrixed cross-functional teams to align experimental workflows across line-functions
  • Lead a team of 4+ in vitro Cellular Immunologists to execute on Candidate Selection and IND-enabling studies
  • Manage and mentor drug discovery project team leaders to guide the team’s pre-clinical strategy to FIH trials.
  • Interface with platform team on novel methods to enhance immune cell antitumor activity, phenotype team to optimally include cell phenotype in pipeline decisions, and clinical team for developing the preclinical plan to support the therapeutic hypothesis for a given indication and antigen target.

Primary Job Requirements:

  • PhD in Immuno-Oncology, Immunology, Cancer Biology, or other relevant field with 12+ years of post-graduate experience in the biotech or pharmaceutical industry
  • Deep and current subject matter expertise in Immune Oncology and Adoptive Cell Therapy
  • NK cell expertise strongly preferred
  • Superior scientific and therapeutic area knowledge and solid understanding of emerging research in portfolio relevant areas
  • Previous experience as a direct people manager and cross-functional drug discovery team leader
  • Demonstrated ability to develop and oversee implementation of scientific activities and management of others directly and in a matrixed structure
  • Excellent oral and written communication skills, including writing, reviewing and editing scientific documents including slide presentations
  • Ability to persuasively convey both ideas and data, and to distil complex issues and ideas down to concise comprehensible terms
  • Able to drive and support key strategic vision

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

atemple@stratacuity.com

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EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystemsinc.com or 844-463-6178.