Principal Scientist, Cancer Biology

Cambridge, MA

Principal Scientist, Cancer Biology 1115722

Job Scope & Purpose:

Our client is combining unprecedented computational power with leading-edge experimental approaches across the fields of biology, biophysics, structural biology, and chemistry. This integration illuminates, for the first time, the full mobility of a protein and provides key insights into how the dynamic nature of a protein’s conformation regulates function. The team is putting this principle into practice, with the aim of accelerating the development of medicines that will make a transformative difference in patients’ lives. 

Primary Job Responsibilities:

  • You will serve as the Biology lead on project teams passionate about developing small molecule modulators of clinically validated targets in cancer
  • You will design and lead biology experiments to assess targets, evaluate candidate small molecules, and support drug discovery
  • You will bring IND writing experience and driving programs towards the clinic
  • Your in vitro experience includes cell line profiling, pathway signaling, understanding of genomic drivers, assay development, compound profiling and progression
  • Your in vivo experience consists of model selection and development, tolerability, PK/PD, efficacy studies, understanding of DMPK and setting appropriate dose levels and interpretation of pharmacology data
  • We value the strength of team development, communication and leadership that inspires motivation to drive quality research with urgency that will better patients’ lives
  • Previous experience managing reports (associates and PhD level scientists), and experience with managing external CROs will allow our teams to keep driving fast and forward
  • You recognize CROs as an extension of your internal team
  • You will interpret, summarize and present research findings at internal and external scientific meetings/conferences
  • You're actively reviewing literature to bring in the newest scientific findings, ideas, and methods/technologies to impact drug discovery projects
  • Excellent communication, attitude, and interpersonal skills are essential for the success of your team and cross functional collaborations

Primary Job Requirements:

  • Ph.D. AND post-doctoral training in cancer biology with demonstrated experience in oncology small molecule drug discovery. with at least 4+ years of experience in biotech/pharma
  • You're driven with a consistent track record of scientific excellence as reflected by high impact, peer reviewed publications and/or patents
  • A confident and thoughtful leader with a successful track record and passion to mentor and develop your direct reports and teammates
  • You are comfortable with — and can thrive in — an environment that is constantly changing, frequently uncertain, and where you're in charge of driving project strategies and progression
  • You have the patience to learn from your team and peers before turning to yourself for all the answers
  • You've got excellent communication, presentation, and inter-personal skills; your energy is infectious and motivates the team

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

atemple@stratacuity.com

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EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystemsinc.com or 844-463-6178.