Senior Research Associate- Biology Department

South San Francisco, CA

SR. RESEARCH ASSOCIATE, CELL BIOLOGY

 

The qualified candidate will join a team focused on developing and executing biochemical and cell-based assays for small molecule lead identification/optimization and deciphering their mechanism of action. In this position you will support drug discovery efforts by providing cell biology expertise.

 

 Responsibilities:
 

  • Culture a variety of cancer cell lines and primary cells
  • Develop and execute cell-based assays in 96-well or 384-well format
  • Analyze molecules’ mechanism of action utilizing flow cytometry, immunofluorescence, western, qPCR, apoptosis or other assays
  • Prepare assay reagents, compound serial dilutions
  • Perform data analysis, reporting and integration with GraphPad Prism, Microsoft Office and other software packages
  • Contribute to or lead lab management activities

Qualifications and Experience:

  • BS or MS in related scientific discipline
  • 3-6 years of industry experience in cell biology and compound profiling
  • Extensive experience in cell culture, compound handling are must have
  • Proficiency in quantitative cell-based assays
  • Familiarity with liquid handling platforms would be a plus
  • Experience with protein analysis by ELISA, MSD ELISA, western, flow cytometry, immunofluorescence
  • Experience with DNA and RNA isolation, qPCR and other RNA analysis techniques
  • Experience with retroviral/lentiviral vectors for generation of stable cell lines and gene knockdown/knockout using shRNA/CRISPR technologies
  • Excellent computer skills combined with data analysis
  • Must be detail oriented, well organized, and have strong communication skills
  • Capable of fully understanding scope of projects
  •  Able to independently troubleshoot and identify solutions to arising issues
  • Excellent teamwork skills and the ability to work under the supervision of a senior member of the biology group, in a fast-paced, multi-disciplinary environment
  • Excellent work ethic, self-motivated, driven, dependable, hardworking

 

 

 

 

 

 

 

 

EEO Employer

Apex is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystemsinc.com or 844-463-6178.