Sr. Scientist, Immunology

Watertown, MA

Sr. Scientist, Immunology 1333380

Location: Watertown, MA (Onsite)

Science: Next generation targeted delivery of biologics

Therapeutic Area: Possible metabolic, muscle, neuro and immunological indications

Job Overview:  Looking for a Sr. Scientist with in vitro and in vivo experience within immunology setting.

Responsibilities:

  • Design and execute challenging projects to advance our drug discovery objectives, support target prioritization. Project tracking (resources/timelines/deliverables) and future people management.
  • Generate novel, testable hypotheses to enable rapid, clear decision making.
  • Design and execute pharmacodynamic and pharmacokinetic characterization of novel experimental therapeutics in animal models, and generation of endpoint data
  • Collaborate with bioinformatics, protein engineers, chemists for platform development and lead optimization; manage CROs and interact with external partners
  • Provide updates on project status to team members and stakeholders
  • Generate and communicate study reports, data packages and related documentation, including for regulatory filings
  • Serve as a scientific expert in immunology and relevant with both internal and external partners.
  • Contribute to the business development evaluation of in-license and out-license opportunities

Qualifications:

  • PhD in Immunology, Biology, Cell biology or similar disciplines, or MS
  • Postdoctoral experience and at least 3 years industry experience
  • Job title will be commensurate with experience
  • Deep knowledge of Immunology and biology of Macrophages, T-cells, B-cells and their involvement in various diseases.
  • Expertise in hands-on rodent pharmacology and preclinical modeling including study design, dosing, necropsy, tissue processing; strong molecular biology and assay development/implementation background (qPCR, bDNA, RNAseq, Flow Cytometry, Western, ELISA, IHC/histology, Fluorescent microscopy).
  • Experience with dosing (PO, IV, SQ, IM, IP) and bleeding (tail nicks, submandibular, intracardiac) of mice, Experience with various tissue and organ collection from mice
  • Excellent verbal and written communication skills, excellent documentation skills and familiarity with electronic notebook, Strong organizational skills
  • Familiar with IACUC and compliance requirements
  • Deep knowledge and broad experience with mammalian cell culture and aseptic technique including cells lines, primary cells, progenitor cells
  • Track record of scientific excellence demonstrated by publications and/or patents. Ability to interact with multidisciplinary teams.
  • Ability to work in a fast-paced and quickly changing environment
  • Scientific creativity, independent thought and decision-making ability.
  • Exceptional problem-solving skills.

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

dhagenbuch@stratacuity.com

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EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at employeeservices@apexsystems.com or 844-463-6178.