(Sr.) Scientist , In Vivo Immunology
Senior Scientist, In Vivo Immunology 1333554
Location: Watertown, MA (Hybrid)
Science/ Focus: Immunology – Cell Therapy
Therapeutic Area: Immunology
Job Focus: Our client is seeking a (Senior) Scientist to support the preclinical pharmacology team. The candidate will be responsible for leading, designing, and executing in-house and outsourced rodent studies to investigate cell therapies in preclinical studies supporting our therapeutic programs in oncology, immunology and hematology.
Responsibilities:
- Selection and characterization of appropriate mouse models for the study of gene-edited cell products
- Design, lead and execute animal studies to assess the pharmacological activity of engineered cell products in preclinical studies to support development of novel cell therapies
- Coordinate and supervise outsourced animal studies at CROs
- Perform various molecular and biochemical assays on tissue samples from preclinical studies
Qualifications:
- PhD in biology, cell biology, immunology, or a related discipline with 0-5+ years of experience, BS or MS with 5+ years of experience in Biotech or pharmaceutical company
- Experience planning and executing mouse studies is a must; experience with dosing of animals via IV, IM, SC routes of administration; experience with live animal imaging
- Familiarity with immuno-compromised, humanized and adoptive transfer mouse models for the study of allogeneic immunological responses
- Experience with tissue harvesting and in vitro assays including flow cytometry and ELISA as well as running a variety of molecular and biochemical assays such as ddPCR, RT-qPCR and luminescence-based assays
About Stratacuity:
Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
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