(Senior) Director, Drug Discovery (Fungal Biology) 2018175 
Location: Cambridge, MA (Onsite)
Science/ Focus: Fungal Biology
Therapeutic Area: Fungal Diseases
Job Overview: This job is seeking a drug discovery leader with expertise in the anti-fungal therapeutic area, who has made substantial contributions to target identification and drug discovery efforts, and has experience in assay and in vivo model development.
Primary Job Responsibilities:

• Lead a research team to develop, optimize, and execute fungal assays to identify and characterize bioactive molecules; design and execute in vitro and in vivo experiments, presenting data to leadership team.
• Strategic leadership and direction for anti-fungal drug target selection, evaluation and prioritization
• Direct the discovery process across preclinical development, clinical candidate selection through to IND filing.
• Collaborate with functional teams, establish PK/PD/efficacy relationship and translational biomarker strategy.

• PhD and 6+ years of drug discovery experience in an industry setting
• Leadership experience in Fungal Biology/Genetics or related subject area
• Proficient in designing and implementing medium to high-throughput assays to assess single agent activity and discover synergistic drug combinations.
• Experience with antifungal drug discovery is highly desirable

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